CLASSIFICATIONS OF DRUGS - 5 Anticancer Drugs (Antineoplastic Drugs) A. Drugs acting directly on cells (Cytotoxic drugs) 1. Alkylating agents Mechlorethamine (Mustine HCl) Nitrogen mustards Cyclophosphamide, Ifosfamide, Chlorambucil, Melphalan. Ethylenimine Thio-TEPA Alkyl sulfonate Busulfan Nitrosoureas Carmustine (BCNU), Lomustine (CCNU), Triazine Dacarbazine (DTIC) 2. Antimetabolites Folate antagonist Methotrexate (Mtx) Purine 6-Mercaptopurine (6-MP), antagonist 6-Thioguanine (6-TG), Azathioprine, Fludarabine Pyrimidine 5-Fluorouracil (5-FU), Cytarabine antagonist (cytosine arabinoside) 3. Vinca alkaloids Vincristine (Oncovin), Vinblastine 4. Taxanes Paclitaxel, Docetaxel 5. Epipodophyllo Etoposide Toxin 6. Camptothecin Topotecan, Irinotecan Analogues 7. Antibiotics Actinomycin D (Dactinomycin) Doxorubicin, Daunorubicin (Rubidomycin), Mitoxantrone Bleomycins, Mitomycin C 8. Miscellaneous Hydroxyurea
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